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This injectable treatment for wrinkles is made from the same neurotoxin (botulinum toxin type A) as Botox. Dysport (formally Reloxin) received the approval of the U.S. Food and Drug Administration (FDA) for use as a wrinkle treatment in the spring of 2009, but it has been smoothing out facial folds and lines in Europe, South America, and elsewhere for several years. Like Botox, this injectable was originally developed in the 1990s to treat neuromuscular disorders.
Dysport is injected directly into the muscles that cause facial wrinkles, temporarily immobilizing them. It specifically targets the glabullar muscles — the ones that form creases on your forehead when you frown.
Dysport diffuses a bit farther from the injection point than Botox: one to three centimeters compared to Botox’s one centimeter. This means that fewer injections are needed, but it also means that the health professional doing the injections must be very skilled to ensure that the drug does not spread to nearby muscles and cause eyelid and/or eyebrow drooping or other unwanted side effects.
Results begin to appear within one to seven days after treatment, with day three being the median. (In other words, half the patients treated see wrinkle-smoothing results before day three, and half see results afterward.) Dysport contains less protein than Botox, so the body tends to break it down more slowly. The studies are mixed, however, about whether the results lasts longer than Botox. A large clinical trial sponsored by Dysport’s manufacturer and published in the March/April 2009 issue of Archives of Facial Plastic Surgery reported that effects lasted more than 13 months in some people. Botox results can last up to four months.
As with Botox, any side effects that develop tend to be minor. Headache may occur, and if the drug diffuses too widely, eyelids or eyebrows may droop. If you choose Dysport to smooth out your wrinkles, be sure you receive treatments from a well-trained and experienced health professional.